{
    "id": 4346,
    "date": "2026-02-24T09:00:15",
    "date_gmt": "2026-02-24T08:00:15",
    "guid": {
        "rendered": "https:\/\/www.phinc-group.com\/?page_id=4346"
    },
    "modified": "2026-03-09T16:55:04",
    "modified_gmt": "2026-03-09T15:55:04",
    "slug": "publications",
    "status": "publish",
    "type": "page",
    "link": "https:\/\/www.phinc-group.com\/fr\/publications\/",
    "title": {
        "rendered": "Publications"
    },
    "content": {
        "rendered": "<div data-elementor-type=\"wp-page\" data-elementor-id=\"4346\" class=\"elementor elementor-4346\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8b5cfd3 e-flex e-con-boxed e-con e-parent\" data-id=\"8b5cfd3\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c718afd e-con-full e-flex e-con e-child\" data-id=\"c718afd\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-af29ebb elementor-widget elementor-widget-heading\" data-id=\"af29ebb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Travaux scientifiques publi\u00e9s avec la participation des experts PhinC<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-09f8d29 phinc-biblio__intro elementor-widget elementor-widget-text-editor\" data-id=\"09f8d29\" data-element_type=\"widget\" data-e-type=\"widget\" id=\"phinc-biblio__intro\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Chez PhinC, nous contribuons activement \u00e0 l\u2019avancement de la mod\u00e9lisation et de la simulation pharmacologique, afin d\u2019\u00e9clairer les d\u00e9cisions de d\u00e9veloppement, d\u2019optimiser les strat\u00e9gies cliniques et d\u2019acc\u00e9l\u00e9rer l\u2019acc\u00e8s des patients \u00e0 de nouvelles th\u00e9rapies. Retrouvez ci-dessous une s\u00e9lection de publications auxquelles nos experts ont pris part ainsi que nos posters scientifiques.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8e4378f elementor-absolute elementor-widget elementor-widget-button\" data-id=\"8e4378f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_position&quot;:&quot;absolute&quot;}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"#posters\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Nos posters \ud83e\udc17<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-581989f elementor-absolute elementor-widget elementor-widget-button\" data-id=\"581989f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_position&quot;:&quot;absolute&quot;}\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"#publi\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Nos publications \ud83e\udc17<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1c9f4bc e-con-full e-flex e-con e-child\" data-id=\"1c9f4bc\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-fe36fdf elementor-widget elementor-widget-image\" data-id=\"fe36fdf\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1200\" height=\"800\" src=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/Cover-publications-1200px-800.png\" class=\"attachment-full size-full wp-image-4657\" alt=\"\" srcset=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/Cover-publications-1200px-800.png 1200w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/Cover-publications-1200px-800-300x200.png 300w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/Cover-publications-1200px-800-1024x683.png 1024w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/Cover-publications-1200px-800-768x512.png 768w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/Cover-publications-1200px-800-18x12.png 18w\" sizes=\"(max-width: 1200px) 100vw, 1200px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0397ffc e-con-full e-flex e-con e-parent\" data-id=\"0397ffc\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-addecba publi elementor-widget elementor-widget-html\" data-id=\"addecba\" data-element_type=\"widget\" data-e-type=\"widget\" id=\"publi\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<!-- PhinC \u2013 Bibliographie (Top 10 + tiroir \"Voir plus\") -->\r\n<section class=\"phinc-biblio\" aria-label=\"PhinC \u2013 R\u00e9f\u00e9rences bibliographiques\">\r\n  <style>\r\n    :root{\r\n      --phinc-blue:#00005f;\r\n      --phinc-pink:#D94B9F;\r\n      --ink:#0F172A;\r\n      --muted:#475569;\r\n      --line:#E6EAF2;\r\n      --bg:#F7F9FC;\r\n      --card:#FFFFFF;\r\n      --radius:18px;\r\n      --shadow: 0 10px 30px rgba(15, 23, 42, .08);\r\n      --max:1180px;\r\n    }\r\n\r\n    .phinc-biblio{\r\n      font-family: inherit;\r\n      color:var(--ink);\r\n      background:\r\n        radial-gradient(900px 480px at 10% 0%, rgba(217, 75, 159, .12), transparent 60%),\r\n        radial-gradient(900px 520px at 90% 10%, rgba(0, 0, 95, .12), transparent 55%),\r\n        linear-gradient(180deg, #fff, var(--bg));\r\n      padding: clamp(28px, 4vw, 56px) 18px;\r\n    }\r\n\r\n    .phinc-biblio__wrap{\r\n      max-width: var(--max);\r\n      margin: 0 auto;\r\n      \r\n    }\r\n\r\n    \/* HERO *\/\r\n    .phinc-biblio__hero{\r\n      display:grid;\r\n      grid-template-columns: 1.20fr .75fr;\r\n      gap: clamp(28px, 7vw, 46px);\r\n      align-items: center;\r\n      margin-bottom: clamp(18px, 3vw, 26px);\r\n      \r\n      \r\n    }\r\n\r\n    @media (max-width: 920px){\r\n      .phinc-biblio__hero{ grid-template-columns: 1fr; }\r\n    }\r\n\r\n    .phinc-biblio__kicker{\r\n      display:inline-flex;\r\n      gap:10px;\r\n      align-items:center;\r\n      font-size: 13px;\r\n      color: var(--muted);\r\n      margin-bottom: 10px;\r\n    }\r\n    .phinc-biblio__dot{\r\n      width:10px;height:10px;border-radius:999px;\r\n      background: radial-gradient(circle at 30% 30%, var(--phinc-pink), var(--phinc-blue));\r\n      box-shadow: 0 6px 18px rgba(0,0,95,.18);\r\n    }\r\n\r\n    .phinc-biblio__title{\r\n      font-size: clamp(22px, 2.6vw, 34px);\r\n      line-height: 1.15;\r\n      \r\n      letter-spacing: -0.02em;\r\n      max-width: 35ch;\r\n    }\r\n\r\n    .phinc-biblio__intro{\r\n      margin: 0 0 14px;\r\n      color: var(--muted);\r\n      font-size: 15.5px;\r\n      line-height: 1.7;\r\n      max-width: 60ch;\r\n    }\r\n\r\n    .phinc-biblio__pillRow{\r\n      display:flex;\r\n      flex-wrap:wrap;\r\n      gap:10px;\r\n      margin-top: 10px;\r\n    }\r\n    .phinc-pill{\r\n      background: rgba(0,0,95,.06);\r\n      border: 1px solid rgba(0,0,95,.10);\r\n      color: var(--phinc-blue);\r\n      border-radius: 999px;\r\n      padding: 8px 12px;\r\n      font-size: 12.5px;\r\n      line-height: 1;\r\n      white-space: nowrap;\r\n    }\r\n    .phinc-pill strong{ font-weight: 700; }\r\n\r\n    .phinc-biblio__imgCard{\r\n      background: var(--card);\r\n      border:1px solid var(--line);\r\n      border-radius: var(--radius);\r\n      box-shadow: var(--shadow);\r\n      overflow:hidden;\r\n    }\r\n    .phinc-biblio__img{\r\n      width:100%;\r\n      aspect-ratio: 600\/415;\r\n      object-fit: cover;\r\n      display:block;\r\n    }\r\n    .phinc-biblio__imgCap{\r\n      padding: 12px 14px;\r\n      font-size: 12.5px;\r\n      color: var(--muted);\r\n      border-top: 1px solid var(--line);\r\n      background: linear-gradient(180deg, #fff, rgba(247,249,252,.9));\r\n    }\r\n\r\n    \/* LIST *\/\r\n    .phinc-biblio__panel{\r\n      background: var(--card);\r\n      border:1px solid var(--line);\r\n      border-radius: var(--radius);\r\n      box-shadow: var(--shadow);\r\n      overflow:hidden;\r\n    }\r\n\r\n    .phinc-biblio__panelHead{\r\n      display:flex;\r\n      align-items: baseline;\r\n      justify-content: space-between;\r\n      gap:14px;\r\n      padding: 16px 18px;\r\n      border-bottom: 1px solid var(--line);\r\n      background: linear-gradient(90deg, rgba(0,0,95,.05), rgba(217,75,159,.04));\r\n    }\r\n\r\n    .phinc-biblio__panelTitle{\r\n      margin:0;\r\n      font-size: 16px;\r\n      letter-spacing: .02em;\r\n      text-transform: uppercase;\r\n      color: var(--phinc-blue);\r\n    }\r\n\r\n    .phinc-biblio__panelHint{\r\n      margin:0;\r\n      font-size: 12.5px;\r\n      color: var(--muted);\r\n      white-space: nowrap;\r\n    }\r\n\r\n    .phinc-biblio__list{\r\n      list-style:none;\r\n      margin:0;\r\n      padding: 0;\r\n    }\r\n\r\n    .phinc-ref{\r\n      padding: 14px 18px;\r\n      border-bottom: 1px solid var(--line);\r\n      display:grid;\r\n      grid-template-columns: 160px 1fr;\r\n      gap: 14px;\r\n      align-items: start;\r\n    }\r\n    .phinc-ref:last-child{ border-bottom:none; }\r\n\r\n    @media (max-width: 720px){\r\n      .phinc-ref{ grid-template-columns: 1fr; }\r\n    }\r\n\r\n    .phinc-ref__meta{\r\n      display:flex;\r\n      flex-direction:column;\r\n      gap:8px;\r\n    }\r\n\r\n    .phinc-badge{\r\n      display:inline-flex;\r\n      align-items:center;\r\n      gap:8px;\r\n      width: fit-content;\r\n      padding: 7px 10px;\r\n      border-radius: 999px;\r\n      background: rgba(0,0,95,.06);\r\n      border:1px solid rgba(0,0,95,.12);\r\n      color: var(--phinc-blue);\r\n      font-size: 12.5px;\r\n      line-height: 1;\r\n      font-weight: 600;\r\n    }\r\n    .phinc-badge .phinc-miniDot{\r\n      width:8px;height:8px;border-radius:999px;\r\n      background: var(--phinc-pink);\r\n      box-shadow: 0 6px 14px rgba(217,75,159,.22);\r\n    }\r\n\r\n    .phinc-ref__source{\r\n      font-size: 12.5px;\r\n      color: var(--muted);\r\n      line-height: 1.3;\r\n    }\r\n\r\n    .phinc-ref__content{\r\n      min-width: 0;\r\n    }\r\n\r\n    .phinc-ref__title{\r\n      margin: 0 0 6px;\r\n      font-size: 15.5px;\r\n      line-height: 1.4;\r\n      font-weight: 700;\r\n      color: var(--ink);\r\n    }\r\n\r\n    .phinc-ref__authors{\r\n      margin:0;\r\n      font-size: 13.5px;\r\n      line-height: 1.55;\r\n      color: var(--muted);\r\n    }\r\n    .phinc-ref__authors strong{ color: var(--ink); font-weight: 700; }\r\n\r\n    \/* DRAWER *\/\r\n    .phinc-drawer{\r\n      border-top: 1px solid var(--line);\r\n      background: linear-gradient(180deg, rgba(247,249,252,.55), #fff);\r\n    }\r\n\r\n    .phinc-drawer summary{\r\n      list-style:none;\r\n      cursor:pointer;\r\n      padding: 14px 18px;\r\n      display:flex;\r\n      align-items:center;\r\n      justify-content:center;\r\n      gap:10px;\r\n      user-select:none;\r\n    }\r\n\r\n    .phinc-drawer summary::-webkit-details-marker{ display:none; }\r\n\r\n    .phinc-btnDrawer{\r\n      display:inline-flex;\r\n      align-items:center;\r\n      gap:10px;\r\n      border-radius: 999px;\r\n      padding: 12px 16px;\r\n      background: var(--phinc-blue);\r\n      color:#fff;\r\n      border: 1px solid rgba(0,0,95,.15);\r\n      box-shadow: 0 10px 22px rgba(0,0,95,.18);\r\n      font-weight: 700;\r\n      font-size: 14px;\r\n      line-height: 1;\r\n      transition: transform .15s ease, box-shadow .15s ease;\r\n    }\r\n    .phinc-btnDrawer:hover{ transform: translateY(-1px); box-shadow: 0 14px 28px rgba(0,0,95,.22); }\r\n    .phinc-btnDrawer .chev{\r\n      width: 10px; height: 10px;\r\n      border-right: 2px solid #fff;\r\n      border-bottom: 2px solid #fff;\r\n      transform: rotate(45deg);\r\n      margin-top: -2px;\r\n      transition: transform .18s ease;\r\n    }\r\n\r\n    .phinc-drawer[open] .phinc-btnDrawer .chev{\r\n      transform: rotate(-135deg);\r\n      margin-top: 3px;\r\n    }\r\n\r\n    .phinc-drawer__inner{\r\n      padding: 0;\r\n    }\r\n\r\n    .phinc-drawer__note{\r\n      padding: 0 18px 14px;\r\n      margin: 0;\r\n      color: var(--muted);\r\n      font-size: 12.5px;\r\n      text-align: center;\r\n    }\r\n  <\/style>\r\n\r\n  <div class=\"phinc-biblio__wrap\">\r\n    \r\n\r\n    <!-- LIST PANEL -->\r\n    <div class=\"phinc-biblio__panel\">\r\n      <div class=\"phinc-biblio__panelHead\">\r\n        <h3 class=\"phinc-biblio__panelTitle\">Publications<\/h3>\r\n        \r\n      <\/div>\r\n\r\n      <!-- TOP 10 -->\r\n      <ul class=\"phinc-biblio__list\" aria-label=\"Top 10 r\u00e9f\u00e9rences (les plus r\u00e9centes)\">\r\n        <li class=\"phinc-ref\">\r\n          <div class=\"phinc-ref__meta\">\r\n            <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Jan 2026<\/span>\r\n            <div class=\"phinc-ref__source\">British Journal of Clinical Pharmacology. 2026. doi: 10.1002\/bcp.70398<\/div>\r\n          <\/div>\r\n          <div class=\"phinc-ref__content\">\r\n            <p class=\"phinc-ref__title\">An open-label, single-arm, dose-escalating concentration\u2013QT\r\nstudy to investigate the cardiac effects and safety of\r\nparoxetine in healthy adults<\/p>\r\n            <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Van Dijkman, S. C., F\u00e9lices, M., Pandurangavittal, B., Ghorpade, S., Easterbrook, C., Zabielski, M., & Della Pasqua, O.<\/p>\r\n          <\/div>\r\n        <\/li>\r\n        <li class=\"phinc-ref\">\r\n          <div class=\"phinc-ref__meta\">\r\n            <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>D\u00e9c 2025<\/span>\r\n            <div class=\"phinc-ref__source\">Jpn J Radiol. 2025;43(12):1962-1970. doi: 10.1007\/s11604-025-01842-1<\/div>\r\n          <\/div>\r\n          <div class=\"phinc-ref__content\">\r\n            <p class=\"phinc-ref__title\">Pharmacokinetics and safety of gadopiclenol in Japanese healthy volunteers.<\/p>\r\n            <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Eto T, Taoka T, Felices M, Pitrou C.<\/p>\r\n          <\/div>\r\n        <\/li>\r\n\r\n        <li class=\"phinc-ref\">\r\n          <div class=\"phinc-ref__meta\">\r\n            <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Nov 2025<\/span>\r\n            <div class=\"phinc-ref__source\">EBioMedicine. 2025 Nov;121:105989. doi: 10.1016\/j.ebiom.2025.105989<\/div>\r\n          <\/div>\r\n          <div class=\"phinc-ref__content\">\r\n            <p class=\"phinc-ref__title\">Comparison of rituximab induction and maintenance regimens in ANCA-associated vasculitis: PK\/PD modelling of ANCA and gammaglobulin levels in real-world patients.<\/p>\r\n            <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Pasquiers B, Blanchet B, Pu\u00e9chal X, Decl\u00e8ves X, Cohen P, Goulvestre C, Casadevall M, Benhabiles I, Vidal M, Ternant D, Terrier B, Puszkiel A.<\/p>\r\n          <\/div>\r\n        <\/li>\r\n<\/ul>\r\n\r\n      <!-- DRAWER: REST -->\r\n      <details class=\"phinc-drawer\" id=\"phincBiblioDrawer\">\r\n        <summary aria-controls=\"phincBiblioMore\">\r\n          <span class=\"phinc-btnDrawer\">\r\n            <span class=\"label\">Voir plus<\/span>\r\n            <span class=\"chev\" aria-hidden=\"true\"><\/span>\r\n          <\/span>\r\n        <\/summary>\r\n\r\n        <div class=\"phinc-drawer__inner\" id=\"phincBiblioMore\">\r\n          \r\n\r\n          <ul class=\"phinc-biblio__list\" aria-label=\"R\u00e9f\u00e9rences suppl\u00e9mentaires\">\r\n        <li class=\"phinc-ref\">\r\n          <div class=\"phinc-ref__meta\">\r\n            <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Nov 2025<\/span>\r\n            <div class=\"phinc-ref__source\">Br J Clin Pharmacol. 2025 Nov 20. doi: 10.1002\/bcp.70328<\/div>\r\n          <\/div>\r\n          <div class=\"phinc-ref__content\">\r\n            <p class=\"phinc-ref__title\">Safety, tolerability and pharmacokinetics of DNDI-6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants.<\/p>\r\n            <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Gillon JY, Delhomme S, Launay D, Blesson S, Braillard S, Maghdooni P, Assmus F, Hoglund R, Tarning J, Loyau S, Arana B, Latreille-Barbier M, Donazzolo Y.<\/p>\r\n          <\/div>\r\n        <\/li>\r\n\r\n        <li class=\"phinc-ref\">\r\n          <div class=\"phinc-ref__meta\">\r\n            <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Nov 2025<\/span>\r\n            <div class=\"phinc-ref__source\">Antimicrob Agents Chemother. 2025;69(11):e00580-25. doi: 10.1128\/aac.00580-25<\/div>\r\n          <\/div>\r\n          <div class=\"phinc-ref__content\">\r\n            <p class=\"phinc-ref__title\">Mass balance, pharmacokinetics, metabolism, and excretion of radiolabeled acoziborole, a potential novel treatment for human African trypanosomiasis, following single microtracer oral dose to humans.<\/p>\r\n            <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Gillon J-Y, Simon F, Sidhu S, Louis M, Launay D, Wauthier V, Pelay-Gimeno M, Andel Lv, Loyau S, Rembry S, Weinling E, Tarral A.<\/p>\r\n          <\/div>\r\n        <\/li>\r\n\r\n        <li class=\"phinc-ref\">\r\n          <div class=\"phinc-ref__meta\">\r\n            <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Sep 2025<\/span>\r\n            <div class=\"phinc-ref__source\">CPT Pharmacometrics Syst Pharmacol. 2025;14(9):1494-1503. doi: 10.1002\/psp4.70071<\/div>\r\n          <\/div>\r\n          <div class=\"phinc-ref__content\">\r\n            <p class=\"phinc-ref__title\">Prediction of a CLDN18.2 Targeted Antibody Drug Conjugate Pharmacokinetics in Cancer Patients Using PBPK Modeling and Simulation.<\/p>\r\n            <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Zunino C, Wang S, Zhang Y, Urdy S, de Witte WEA, Decl\u00e8ves X, Puszkiel A, Djebli N.<\/p>\r\n          <\/div>\r\n        <\/li>\r\n\r\n        <li class=\"phinc-ref\">\r\n          <div class=\"phinc-ref__meta\">\r\n            <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Juil 2025<\/span>\r\n            <div class=\"phinc-ref__source\">Clin Transl Sci. 2025;18(7):e70305. doi: 10.1111\/cts.70305<\/div>\r\n          <\/div>\r\n          <div class=\"phinc-ref__content\">\r\n            <p class=\"phinc-ref__title\">Concentration-Response Analysis of the Combination of Pyronaridine and Piperaquine on Corrected QT Interval From a Randomized, Double-Blind, Placebo-Controlled Study in Healthy Adults of African Sub-Saharan Origin.<\/p>\r\n            <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Felices M, Borghini-Fuhrer I, Abla N, Chalon S.<\/p>\r\n          <\/div>\r\n        <\/li>\r\n\r\n        <li class=\"phinc-ref\">\r\n          <div class=\"phinc-ref__meta\">\r\n            <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Mar 2024<\/span>\r\n            <div class=\"phinc-ref__source\">Translational Therapeutics<\/div>\r\n          <\/div>\r\n          <div class=\"phinc-ref__content\">\r\n            <p class=\"phinc-ref__title\">Extending the dosing intervals of nivolumab: model-based simulations in unselected cancer patients.<\/p>\r\n            <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Puszkiel, A., Bianconi, G., Pasquiers, B. et al.<\/p>\r\n          <\/div>\r\n        <\/li>\r\n        <li class=\"phinc-ref\">\r\n          <div class=\"phinc-ref__meta\">\r\n            <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Jan 2024<\/span>\r\n            <div class=\"phinc-ref__source\">Pharmaceutics. 2024 Jan 10;16(1):96. doi: 10.3390\/pharmaceutics16010096.<\/div>\r\n          <\/div>\r\n          <div class=\"phinc-ref__content\">\r\n            <p class=\"phinc-ref__title\">PBPK Modeling Approach to Predict the Behavior of Drugs Cleared by Metabolism in Pregnant Subjects and Fetuses.<\/p>\r\n            <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Le Merdy M, Szeto KX, Perrier J, Bolger MB, Lukacova V.<\/p>\r\n          <\/div>\r\n        <\/li>\r\n\r\n        <li class=\"phinc-ref\">\r\n          <div class=\"phinc-ref__meta\">\r\n            <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Sep 2023<\/span>\r\n            <div class=\"phinc-ref__source\">Clin Transl Sci 16(11):2222-2235. doi: 10.1111\/cts.13622<\/div>\r\n          <\/div>\r\n          <div class=\"phinc-ref__content\">\r\n            <p class=\"phinc-ref__title\">Drug-drug interaction prediction of ziritaxestat using a physiologically based enzyme and transporter pharmacokinetic network interaction model.<\/p>\r\n            <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Jeremy Perrier, Virginie Gualano, Eric Helmer, Florence Namour, Viera Lukacova, Amit Taneja.<\/p>\r\n          <\/div>\r\n        <\/li>\r\n\r\n        <li class=\"phinc-ref\">\r\n          <div class=\"phinc-ref__meta\">\r\n            <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Ao\u00fbt 2023<\/span>\r\n            <div class=\"phinc-ref__source\">Pharmaceutics<\/div>\r\n          <\/div>\r\n          <div class=\"phinc-ref__content\">\r\n            <p class=\"phinc-ref__title\">Translation of Monoclonal Antibodies Pharmacokinetics from Animal to Human Using Physiologically Based Modeling in Open Systems Pharmacology (OSP) Suite: A Retrospective Analysis of Bevacizumab.<\/p>\r\n            <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Pasquiers B, Benamara S, Felices M, Ternant D, Decl\u00e8ves X, Puszkiel A.<\/p>\r\n          <\/div>\r\n        <\/li>\r\n\r\n        <li class=\"phinc-ref\">\r\n          <div class=\"phinc-ref__meta\">\r\n            <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Ao\u00fbt 2023<\/span>\r\n            <div class=\"phinc-ref__source\">Investigative Radiology \u2013 Volume 57, Issue 8, p 510-516<\/div>\r\n          <\/div>\r\n          <div class=\"phinc-ref__content\">\r\n            <p class=\"phinc-ref__title\">Pharmacokinetics, Safety, and Efficacy of Gadopiclenol in Pediatric Patients Aged 2 to 17 Years.<\/p>\r\n            <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Jurkiewicz E, Tsvetkova S, Grinberg A, Pasquiers B.<\/p>\r\n          <\/div>\r\n        <\/li>\r\n      \r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>2023<\/span>\r\n                <div class=\"phinc-ref__source\">Clinical Pharmacokinetics<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Determination of the optimal single dose treatment for Acoziborole, a novel drug for the treatment of human African trypanosomiasis: First-in-human study.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Tarral, A., Hovsepian, L., Duvauchelle, T., Donazzolo, Y., Latreille, M., Felices, M., Gualano, V., Delhomme, S., Valverde Mordt, O., Blesson, S., Voiriot, P., &amp; Strub-Wourgaft, N.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Mar 2023<\/span>\r\n                <div class=\"phinc-ref__source\">Br J Clin Pharmacol. doi: 10.1111\/bcp.15545.<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Bioavailability and cardiovascular effects of adrenaline administered by Anapen 500 \u03bcg auto-injector in healthy volunteers.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Duvauchelle T, Robert P, Donazzolo Y, Loyau S, Orlandini B, Lehert P, Lecomte JM, Schwartz JC.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Oct 2022<\/span>\r\n                <div class=\"phinc-ref__source\">Int J Mol Sci. 2022 doi: 10.3390\/ijms232112754.<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Review of the Existing Translational Pharmacokinetics Modeling Approaches Specific to Monoclonal Antibodies (mAbs) to Support the First-In-Human (FIH) Dose Selectio.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Hirt D, Oualha M, Pasquiers B, Blanot S, Rubinstazjn R, Glorion C, Messaoudi SE, Drummond D, Lopez V, Toubiana J, B\u00e9ranger A, Boujaafar S, Zheng Y, Capito C, Winter S, L\u00e9ger PL, Berthaud R, Gana I, Foissac F, Tr\u00e9luyer JM, Bouazza N, Benaboud S.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Nov 2021<\/span>\r\n                <div class=\"phinc-ref__source\">Eur J Clin Pharmacol, 77(11)<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Population pharmacokinetics of intravenous and oral ciprofloxacin in children to optimize dosing regimens.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Hirt D, Oualha M, Pasquiers B, Blanot S, Rubinstazjn R, Glorion C, Messaoudi SE, Drummond D, Lopez V, Toubiana J, B\u00e9ranger A, Boujaafar S, Zheng Y, Capito C, Winter S, L\u00e9ger PL, Berthaud R, Gana I, Foissac F, Tr\u00e9luyer JM, Bouazza N, Benaboud S.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Mars 2021<\/span>\r\n                <div class=\"phinc-ref__source\">Antimicrob Agents Chemother. 65(4):e02150-19. doi: 10.1128\/AAC.02150-19<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Drug-Drug Interaction Study of Benznidazole and E1224 in Healthy Male Volunteers.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Isabela Ribeiro, Bethania Blum, Jayme Fernandes, Glaucia Santina, Makoto Asada, Michael Everson, Edgar Schuck, Ethel Feleder, Eric Evene, Virginie Gualano.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>2021<\/span>\r\n                <div class=\"phinc-ref__source\">The AAPS Journal, 23(4), 89<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">PBPK Modeling Approach to Predict the Behavior of Drugs Cleared by Kidney in Pregnant Subjects and Fetus.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Szeto, K. X., Le Merdy, M., Dupont, B., Bolger, M. B., &amp; Lukacova, V.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>2020<\/span>\r\n                <div class=\"phinc-ref__source\">European Journal of Clinical Pharmacology, 76(10), 1393-1400. doi:10.1007\/s00228-020-02929-6<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Absence of QTc prolongation in a thorough QT study with imeglimin, a first in class oral agent for type 2 diabetes mellitus.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Dubourg, J., Perrimond-Dauchy, S., Felices, M., Bolze, S., Voiriot, P., &amp; Fouqueray, P.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>2020<\/span>\r\n                <div class=\"phinc-ref__source\">Br J Clin Pharmacol, 86(11), 2174-2181. doi:10.1111\/bcp.14309<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Randomized study of the effect of gadopiclenol, a new gadolinium-based contrast agent, on the QTc interval in healthy subjects.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Funck-Brentano, C., Felices, M., Fur, N. L., Dubourdieu, C., Desch\u00e9, P., Vanhoutte, F., &amp; Voiriot, P.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n             <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Jul. 2019<\/span>\r\n                <div class=\"phinc-ref__source\">Sci Rep. doi: 10.1038 s41598-018-37113-5.<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Evaluation of the effects on the QT-interval of 4 artemisinin-based combination therapies with a correction-free and heart rate-free method.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Funck-Brentano C, Ouologuem N, Duparc S, Felices M, Sirima SB, Sagara I, Soulama I, Ouedraogo JB, Beavogui AH, Borghini-Fuhrer I, Khan Y, Djimd\u00e9 AA, Voiriot P.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Jul. 2019<\/span>\r\n                <div class=\"phinc-ref__source\">Clinical and Translational Science. doi:10.1111\/cts.12678<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">First-in-Human, Healthy Volunteers Integrated Protocol of ETC-206, an Oral Mnk 1\/2 Kinase Inhibitor Oncology Drug.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Teneggi, V., Novotny-Diermayr, V., Lee, L.H., Yasin, M., Yeo, P., Ethirajulu, K., Gan, S.B.H., Blanchard, S.E., Nellore, R., Umrani, D.N., Gomeni, R., Teck, D.L.W., Li, G., Lu, Q.S., Cao, Y.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>Jan. 2019<\/span>\r\n                <div class=\"phinc-ref__source\">Sci Rep. doi:10.1038\/s41598-018-37112-6<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Effects of Dihydroartemisinin-Piperaquine Phosphate and Artemether-Lumefantrine on QTc Interval Prolongation.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Funck-Brentano C, Bacchieri A, Valentini G, Pace S, Tommasini S, Voiriot P, Ubben D, Duparc S, Evene E, Felices M, Corsi M.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>2018<\/span>\r\n                <div class=\"phinc-ref__source\">J Allergy Clin Immunol Pract, 6(4):1257-1263. doi: 10.1016\/j.jaip.2017.09.021<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Bioavailability and Cardiovascular Effects of Adrenaline Administered by Anapen Autoinjector in Healthy Volunteers.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Thierry Duvauchelle, Philippe Robert, Yves Donazzolo, Sabrina Loyau, Bernard Orlandini, Philippe Lehert, Jeanne-Marie Lecomte, Jean-Charles Schwartz.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>2014<\/span>\r\n                <div class=\"phinc-ref__source\">Cancer Res 1 October 2014. doi: 10.1158\/1538-7445.AM2014-900<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Abstract 900: Computing tumor growth rate across pre- and post-treatment periods uncovers anti-tumor activity in patients treated by a pan-CDK inhibitor (BAY1000394)<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Antoine Hollebecque; Charles Ferte; Gerard Nitenberg; Mathieu Felices; Alexandre Durand-Salmon; Matthias Ocker; Jean-Charles Soria<\/p>\r\n              <\/div>\r\n            <\/li>\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>2014<\/span>\r\n                <div class=\"phinc-ref__source\">Vaccine. 32(46):6138-45. doi: 10.1016\/j.vaccine.2014.08.070<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Efficacy of ABX196, a new NKT agonist, in prophylactic human vaccination.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Josianne Nitcheu Tefit, Sandrine Crab\u00e9, Bernard Orlandini, Haylene Nell, Albert Bendelac, Shenglou Deng, Paul B Savage, Luc Teyton, Vincent Serra.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>2008<\/span>\r\n                <div class=\"phinc-ref__source\">J Steroid Biochem Mol Biol, 109(1-2):177-84<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Pharmacokinetic study of a new testosterone-in-adhesive matrix patch applied every 2 days to hypogonadal men.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Raynaud JP, Aumonier C, Gualano V, Betea D, Beckers A.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>2007<\/span>\r\n                <div class=\"phinc-ref__source\">Clin Pharm; Ther., 81(3):401-5<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Safety and pharmacokinetics of paracetamol following intravenous administration of 5 g during the first 24 h with a 2-g starting dose.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Gregoire N, Hovsepian L, Gualano V, Ev\u00e8ne E, Dufour G, Gendron A.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>2004<\/span>\r\n                <div class=\"phinc-ref__source\">Clin Drug Invest. 24(12):739-747<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Bioequivalence study of two Ibuprofen formulations administered intravenously in healthy male volunteers.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Chassard D, Geneteau A, Gualano V, Brault M.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>2004<\/span>\r\n                <div class=\"phinc-ref__source\">J Clin Pharmacol. 44:1114-24<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Population pharmacokinetics of ibuprofen enantiomers in very premature neonates.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Gr\u00e9goire N, Gualano V, Geneteau A, Millerioux L, Brault M, Mignot A, Roze J.C.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>2003<\/span>\r\n                <div class=\"phinc-ref__source\">Arzneimittelforschung; 53(3):201-5<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Pharmacokinetics and tolerability of prulifloxacin after single oral administration.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Picollo R, Brion N, Gualano V, Millerioux L, Marchetti M, Rosignoli MT, Dionisio P.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>2002<\/span>\r\n                <div class=\"phinc-ref__source\">Chemotherapy. 48(3):116-21<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Multiple-dose pharmacokinetics and excretion balance of gatifloxacin, a new fluoroquinolone antibiotic, following oral administration to healthy Caucasian volunteers.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Mignot A, Guillaume M, Brault M, Gualano V, Millerioux L, Gohler K, Stahlberg HJ.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>1999<\/span>\r\n                <div class=\"phinc-ref__source\">Clin Drug Investig. 17(6):475-82<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Comparative bioavailability of two oral nimodipine formulations after administration to 24 healthy volunteers.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Gualano V, Ntssikoussalabongui B, Mignot A, Duvauchelle T, Felices M, Guillaume M, Orlandini B, Holguin J, Alca\u00efde A.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>1998<\/span>\r\n                <div class=\"phinc-ref__source\">Clin Drug Investigation, 16:141\u2013149<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Comparative bioavailability study of two omeprazole formulations after single and repeated administrations.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Duvauchelle T., Mill\u00e9rioux L., Gualano V., Ev\u00e8ne E., Alca\u00efde A.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>1996<\/span>\r\n                <div class=\"phinc-ref__source\">J Chromatogr A. 729(1-2):309-14<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">High-performance liquid chromatographic determination of baclofen in human plasma.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Millerioux L, Brault M, Gualano V, Mignot A.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>1994<\/span>\r\n                <div class=\"phinc-ref__source\">Nephron. 66(2):157-61<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Pharmacokinetics of carboplatin in a patient suffering from advanced ovarian carcinoma with hemodialysis-dependent renal insufficiency.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Chatelut E, Rostaing L, Gualano V, Vissac T, De Forni M, Ton-That H, Suc JM, Houin G, Canal P.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>1993<\/span>\r\n                <div class=\"phinc-ref__source\">Bull Cancer 80(5):408-17<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Continuous double administration of 5 fluorouracil (intravenous and intraperitoneal) modulated by folinic acid: phase I clinical study and pharmacokinetics in patients with intra-abdominal developing cancers.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Forni M, Gualano V, Canal P, Martel P, Izar-Soum F, Chevreau C, Soulie P, Roche H, Bugat R.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>1993<\/span>\r\n                <div class=\"phinc-ref__source\">Cancer Chemother Pharmacol. 32(5):379-84<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Cellular pharmacokinetics of doxorubicin in patients with chronic lymphocytic leukemia: comparison of bolus administration and continuous infusion.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Muller C, Chatelut E, Gualano V, De Forni M, Huguet F, Attal M, Canal P, Laurent G.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n\r\n            <li class=\"phinc-ref\">\r\n              <div class=\"phinc-ref__meta\">\r\n                <span class=\"phinc-badge\"><span class=\"phinc-miniDot\" aria-hidden=\"true\"><\/span>1991<\/span>\r\n                <div class=\"phinc-ref__source\">Clin Neuropharmacol. 14(5):432-7<\/div>\r\n              <\/div>\r\n              <div class=\"phinc-ref__content\">\r\n                <p class=\"phinc-ref__title\">Sublingual apomorphine in Parkinson\u2019s disease: a clinical and pharmacokinetic study.<\/p>\r\n                <p class=\"phinc-ref__authors\"><strong>Scientists :<\/strong> Montastruc JL, Rascol O, Senard JM, Gualano V, Bagheri H, Houin G, Lees A, Rascol A.<\/p>\r\n              <\/div>\r\n            <\/li>\r\n          <\/ul>\r\n        <\/div>\r\n      <\/details>\r\n    <\/div>\r\n  <\/div>\r\n\r\n  <script>\r\n    (function(){\r\n      const d = document.getElementById('phincBiblioDrawer');\r\n      if(!d) return;\r\n\r\n      const label = d.querySelector('.phinc-btnDrawer .label');\r\n      const sync = () => { if(label) label.textContent = d.open ? 'Voir moins' : 'Voir plus'; };\r\n\r\n      sync();\r\n      d.addEventListener('toggle', sync);\r\n    })();\r\n  <\/script>\r\n<\/section>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b2c0d0f e-flex e-con-boxed e-con e-parent\" data-id=\"b2c0d0f\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c9fd456 posters elementor-widget elementor-widget-heading\" data-id=\"c9fd456\" data-element_type=\"widget\" data-e-type=\"widget\" id=\"posters\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Nos posters<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c907974 e-flex e-con-boxed e-con e-parent\" data-id=\"c907974\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-6a86952 e-con-full e-flex e-con e-child\" data-id=\"6a86952\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-9b94b12 e-con-full e-flex e-con e-child\" data-id=\"9b94b12\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-86d54c6 elementor-widget elementor-widget-image\" data-id=\"86d54c6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"500\" height=\"300\" src=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1.jpg\" class=\"attachment-large size-large wp-image-4637\" alt=\"\" srcset=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1.jpg 500w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1-300x180.jpg 300w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1-18x12.jpg 18w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-bebdf45 e-con-full e-flex e-con e-child\" data-id=\"bebdf45\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3285a80 elementor-button-info elementor-widget elementor-widget-button\" data-id=\"3285a80\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Poster<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-61b04e5 elementor-widget elementor-widget-heading\" data-id=\"61b04e5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Prediction of target-mediated PK profile of Bevacizumab in cancer patients using PBPK modeling<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f47e58e e-con-full e-flex e-con e-child\" data-id=\"f47e58e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4f1296a elementor-align-left elementor-widget__width-auto btn_more elementor-widget elementor-widget-button\" data-id=\"4f1296a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2025\/04\/Poster-GMP-Salih-mAbs-2022.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Consulter<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1a7006b e-con-full e-flex e-con e-child\" data-id=\"1a7006b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-0a60986 e-con-full e-flex e-con e-child\" data-id=\"0a60986\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c77727b elementor-widget elementor-widget-image\" data-id=\"c77727b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"500\" height=\"300\" src=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1.jpg\" class=\"attachment-full size-full wp-image-4637\" alt=\"\" srcset=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1.jpg 500w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1-300x180.jpg 300w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1-18x12.jpg 18w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ea0b64a e-con-full e-flex e-con e-child\" data-id=\"ea0b64a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6ba8689 elementor-button-info elementor-widget elementor-widget-button\" data-id=\"6ba8689\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Poster<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5c0ed37 elementor-widget elementor-widget-heading\" data-id=\"5c0ed37\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Cardiac Safety of MMV533, a new An malarial Drug Candidate: Concentration on-QTc Analysis from the First-In-Human\u200b<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-19f82bd e-con-full e-flex e-con e-child\" data-id=\"19f82bd\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2299074 elementor-align-left elementor-widget__width-auto btn_more elementor-widget elementor-widget-button\" data-id=\"2299074\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2025\/04\/EACPT-2024_MMV533-QTc-POSTER.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Consulter<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2ad9f8f e-con-full e-flex e-con e-child\" data-id=\"2ad9f8f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-cdf2909 e-con-full e-flex e-con e-child\" data-id=\"cdf2909\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c7d507d elementor-widget elementor-widget-image\" data-id=\"c7d507d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"500\" height=\"300\" src=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1.jpg\" class=\"attachment-large size-large wp-image-4637\" alt=\"\" srcset=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1.jpg 500w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1-300x180.jpg 300w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1-18x12.jpg 18w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0dcb59d e-con-full e-flex e-con e-child\" data-id=\"0dcb59d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4847360 elementor-button-info elementor-widget elementor-widget-button\" data-id=\"4847360\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Poster<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5d9e085 elementor-widget elementor-widget-heading\" data-id=\"5d9e085\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Developing a mechanistic in vitro-in vivo relationship (IVIVR) for drug A using Physiologically-based pharmacokinetic modeling<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-121c340 e-con-full e-flex e-con e-child\" data-id=\"121c340\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-08605d2 elementor-align-left elementor-widget__width-auto btn_more elementor-widget elementor-widget-button\" data-id=\"08605d2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2025\/04\/Poster_IVIVR_Relationship.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Consulter<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a55c32f e-con-full e-flex e-con e-child\" data-id=\"a55c32f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-d7a3076 e-con-full e-flex e-con e-child\" data-id=\"d7a3076\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5cb9265 elementor-widget elementor-widget-image\" data-id=\"5cb9265\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"500\" height=\"300\" src=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1.jpg\" class=\"attachment-full size-full wp-image-4637\" alt=\"\" srcset=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1.jpg 500w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1-300x180.jpg 300w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1-18x12.jpg 18w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-20f0a35 e-con-full e-flex e-con e-child\" data-id=\"20f0a35\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-70c1eea elementor-button-info elementor-widget elementor-widget-button\" data-id=\"70c1eea\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Poster<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-06e010d elementor-widget elementor-widget-heading\" data-id=\"06e010d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Translational PK of bevacizumab between monkey and human using PBPK modeling<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-41f9348 e-con-full e-flex e-con e-child\" data-id=\"41f9348\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2a1b561 elementor-align-left elementor-widget__width-auto btn_more elementor-widget elementor-widget-button\" data-id=\"2a1b561\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2025\/04\/Poster-GMP-Blaise-2022-_FINAL.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Consulter<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-abe3962 e-flex e-con-boxed e-con e-parent\" data-id=\"abe3962\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-5197cbd e-con-full e-flex e-con e-child\" data-id=\"5197cbd\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-b85822c e-con-full e-flex e-con e-child\" data-id=\"b85822c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ebcf421 elementor-widget elementor-widget-image\" data-id=\"ebcf421\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"500\" height=\"300\" src=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1.jpg\" class=\"attachment-full size-full wp-image-4637\" alt=\"\" srcset=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1.jpg 500w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1-300x180.jpg 300w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1-18x12.jpg 18w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c593632 e-con-full e-flex e-con e-child\" data-id=\"c593632\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a96873a elementor-button-info elementor-widget elementor-widget-button\" data-id=\"a96873a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Poster<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f84be93 elementor-widget elementor-widget-heading\" data-id=\"f84be93\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Prediction of a Claudin 18.2 targeted Antibody Drug Conjugate Pharmacokinetics in Cancer Patients Using PBPK Modeling and Simulation<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4f7ee3f e-con-full e-flex e-con e-child\" data-id=\"4f7ee3f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ebeb955 elementor-align-left elementor-widget__width-auto btn_more elementor-widget elementor-widget-button\" data-id=\"ebeb955\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2025\/04\/Poster-GMP_2024_Luzsana_PhinC.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Consulter<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-da59069 e-con-full e-flex e-con e-child\" data-id=\"da59069\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-0c14ba2 e-con-full e-flex e-con e-child\" data-id=\"0c14ba2\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-cc2a19d elementor-widget elementor-widget-image\" data-id=\"cc2a19d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"500\" height=\"300\" src=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1.jpg\" class=\"attachment-full size-full wp-image-4637\" alt=\"\" srcset=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1.jpg 500w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1-300x180.jpg 300w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1-18x12.jpg 18w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7674c87 e-con-full e-flex e-con e-child\" data-id=\"7674c87\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c501a7b elementor-button-info elementor-widget elementor-widget-button\" data-id=\"c501a7b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Poster<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ae0cef3 elementor-widget elementor-widget-heading\" data-id=\"ae0cef3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Development of a mechanistic absorption model for a monoclonal antibody administered subcutaneously<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cb199be e-con-full e-flex e-con e-child\" data-id=\"cb199be\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d7925f8 elementor-align-left elementor-widget__width-auto btn_more elementor-widget elementor-widget-button\" data-id=\"d7925f8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.phinc-group.com\/fr\/download\/2014\/?tmstv=1738762950&#038;v=2015\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Consulter<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-bb8b60a e-con-full e-flex e-con e-child\" data-id=\"bb8b60a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-ba66e7f e-con-full e-flex e-con e-child\" data-id=\"ba66e7f\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a7895c5 elementor-widget elementor-widget-image\" data-id=\"a7895c5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"500\" height=\"300\" src=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1.jpg\" class=\"attachment-full size-full wp-image-4637\" alt=\"\" srcset=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1.jpg 500w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1-300x180.jpg 300w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1-18x12.jpg 18w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b2bb149 e-con-full e-flex e-con e-child\" data-id=\"b2bb149\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-894ee4f elementor-button-info elementor-widget elementor-widget-button\" data-id=\"894ee4f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Poster<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-45e46d0 elementor-widget elementor-widget-heading\" data-id=\"45e46d0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Development of a kidney transporter-mediated drug-drug interaction between cimetidine and ranitidine using PBPK modeling<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e0772fa e-con-full e-flex e-con e-child\" data-id=\"e0772fa\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-770505c elementor-align-left elementor-widget__width-auto btn_more elementor-widget elementor-widget-button\" data-id=\"770505c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2025\/04\/Poster-Development-of-kidney-DDI-cimetidine-ranitidine.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Consulter<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b011df6 e-con-full e-flex e-con e-child\" data-id=\"b011df6\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-f53359b e-con-full e-flex e-con e-child\" data-id=\"f53359b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-866f03d elementor-widget elementor-widget-image\" data-id=\"866f03d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"500\" height=\"300\" src=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1.jpg\" class=\"attachment-full size-full wp-image-4637\" alt=\"\" srcset=\"https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1.jpg 500w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1-300x180.jpg 300w, https:\/\/www.phinc-group.com\/wp-content\/uploads\/2026\/03\/View-poster-500x300-1-18x12.jpg 18w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7d12502 e-con-full e-flex e-con e-child\" data-id=\"7d12502\" 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